Nfl Schedule 49ers 2025. The schedule includes the opponents, dates, and results. View the 2025 san francisco 49ers schedule at fbschedules.com.
In week 18, two games will be played on saturday (4:30 pm et and 8:15 pm et) with the remainder to be played on sunday afternoon (1:00 pm et and 4:25 pm et) and one. Future scheduling is determined using the nfl’s system as described at wikipedia.